Preheat the oven to 450 degrees F.
Once the oven is at temperature, set a cast-iron skillet on the middle rack and leave it for 20 minutes.
Meanwhile, in a blender, combine the flour, milk, sugar, cinnamon, nutmeg, vanilla extract, salt, eggs and lemon zest and juice. Blend until foamy, about 1 minute.
Spray the preheated skillet with canola spray and pour in the batter. Bake until the pancake is puffy and lightly browned, 15 to 20 minutes.
Garnish with powdered sugar and berries, as desired.