Joanne Chang is not your average baker. With a degree in applied mathematics from Harvard University, she is the brain behind the famous "Sticky Sticky Buns" of Flour Bakery in Boston. Because of her expert sweet tooth and Ivy-League intellect, she's been told she's starring in a special called "The Science of Sweets". What she doesn't know is that there is an unexpected X-Factor: Bobby Flay is showing up to challenge her to a sticky-bun Throwdown. Will the Iron Chef get schooled by this bun-baking genius, or can Bobby's sticky buns add up to number one?