New Orleans, Louisiana is the home of Muffaletta - a sandwich made with Italian meats, cheeses, and a special olive salad - and no place delivers the Muffaletta better than Serio's Deli. Owners Jack and Mike Serio are now ready to present their three-generations-old recipe to Food Network, for what they think is a TV special on deli sandwiches called "Order Up!" Little do they know that a Throwdown is on the menu, and Bobby Flay is working on a Muffaletta of his own. Will the Serio brothers distinguish themselves as Muffaletta Masters, or will the Iron Chef give them a hard time in the Big Easy? It's a Mardi-Gras atmosphere for the ultimate sandwich showdown!