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For the meatloaf: Preheat the oven to 350 degrees F.
In a large mixing bowl, add the 3 combined pounds of ground meat, the seasoned breadcrumbs and eggs. Mix this all together with your hands until the consistency is uniform.
In a small bowl, combine the garlic powder, onion powder, paprika, salt, black pepper and celery seed for seasoning the meatloaf. Add this seasoning to the large mixing bowl and mix it into the meat well.
Take the ground meat mixture out of the mixing bowl and shape it into a loaf on a baking sheet. Gently pour the tomato sauce over the top of the meatloaf. Bake for 1 hour and 30 minutes and serve warm.